Issue 121 • August 2022 How much does it hurt—measuring pain in clinical trials Tracing the rise of orphan drug designations over almost 40 years Heart failure: charting clinical trials in the past decade In association with Genomic projects exploit scale as clinical applications play catch-up New studies on gene signatures and chromosomal instability using samples from large databases add insight to their clinical applicability In association with 07/25/2022 08:59:57