One of the most efficient screening assay designs is an arranged series of small Overlapping Peptides, each with a defined length and offset to maximise usefulness.

Finding T-cell Epitopes

The properties of T-cell epitopes lend themselves to studies utilising Overlapping PepSet™ Peptide Libraries. These short, linear sequences from the primary protein can be mapped easily with unmodified, unpurified peptide libraries.

Research Strategies

T-cell epitope mapping
Antibody epitope mapping
Antigen epitope mapping
Screening proteins to identify substrates
Searching proteins for binding sites
T-cell stimulation assays

With minor modifications, the already versatile Overlapping Peptide Libraries can be diversified to include applications in immunology, pharmacology, biochemistry, drug discovery and development, immunodiagnostic testing and vaccine development, to name a few. There are virtually limitless options for modifications, including biotinylation and bioconjugation.

Fast and Direct Answers

The Overlapping Peptide design allows for thorough searching of the primary protein sequence without the difficulty of having to synthesise and utilise a peptide of comparable length. These PepSets™ can be used immediately for fast results.