Softigel is Procaps' strategic business
Softigel is Procaps' strategic business unit for contract development services, supporting healthcare and related businesses by developing, manufacturing and commercializing pharmaceutical products, nutritional supplements, veterinary formulations in softgel patented technologies, offering single and multiple drug dosage systems.
Our differentiating strengths enable us to move into more difficult-to-produce compounds, formulations, dosage forms, and non-traditional manufacturing processes where few competitors can follow.
Our seven cutting-edge facilities along South America house a fully integrated product development services (PDS) unit and cover all product lifecycle phases from early development to commercial in the same plant. Our new pilot plant facility for the manufacturing of experimental and pilot batches for softgels, liquids and tablets, uses equipment that can replicate both lab-scale and small-scale GMP batches, up to full-scale commercial GMP.
Our product development team provides customers with access to formulation development, process development, Clinical trial manufacturing, and scale-up services, analytical development and regulatory support for a range of softgel types, new technologies and other drug delivery forms, from Phase I scale, through registration, to large scale commercial production.
01 / Products & Services
We offer more than traditional softgels. Softigel services include everything from a single unit dosage form, to multiple delivery systems in a single dose.
Softgel development partner
We are your ideal partner for the development of softgels for a number of reasons, such as:
- Our softgels are pharmaceutically acceptable for oral use
- Softigel products are sufficiently soluble to dissolve a given dose in a small volume
- We produce a fill formulation that is stable and compatible with shell materials
- Softigel prevents precipitation of solubilized compounds during manufacturing, shelf-life, as well as upon contact with the aqueous environment in vitro (dissolution) and in vivo (GIT)
- One or two colours available
- Ribbon printing
With our wide experience in project managing, we assure that our customers’ projects will be handled efficiently, providing confidence in the accuracy of our timelines, with efficient tools to facilitate timely, transparent communication regarding project status.
Our ability to successfully launch around 50 new products each year illustrates our capabilities and proves that we give every project individual attention.
Fixed dose combinations in Softgel - Introducing Unigel ™
Unigel is a unique oral dosage form that allows having tablets, capsules, granules or pellets inside a single, larger soft gelatin capsule. It is the only patented technique available for fixed dose combinations which incorporates the benefit of the soft gelatin capsule dosage form.
Benefits of UnigelTM include:
- Single or Multiple active ingredients with different release profiles
- Multiple active ingredients with chemical incompatibility concerns
- Multiple active ingredients where at least one is a liquid or a semisolid
02 / Gelatin coated tablets for better consumer acceptance - G-tabs™
G-tabsTM is a Patented technology for tablets coated with one or two-toned color gelatin, printed or not printed.
Benefits of G-tabsTM include:
- Easy to swallow
- Custom branding
- Preventing counterfeiting
- Unpleasant flavor and odor masking
- Improve stability of photosensitive APIs
- Looks like a softgel
They are also ideal for the following applications:
- APIs that can irritate the esophageal mucosa when they are incorporated in an immediate release tablet, such as bisphosphonates
- Double blind clinical studies
- Improving stability of photosensitive APIs, preventing counterfeiting, custom-branding, easy recognition of tampering
03 / Softgels free from animal derivatives - Versagels™
Versagels are polysaccharide-based soft shell capsules, free from animal derivatives which contain carrageenan, modified starch, plasticizers and water.
Versagels create opportunities to bring more products to market, better acceptance by religious and vegetarian groups, as well as compatibility with a broader range of high pH fill formulations.
04 / Chewable softgel technology with Chewgels™
Softigel chewable softgels come in different shapes and flavours, offering a solution and line extension to existing products. The benefits of chewable softgels include:
- Convenient administration without water
- Portable dosage form that eliminates messy liquids
- Pleasant taste, helping to mask tastes and odours
- The ability to be formulated into a range of textures
- Numerous nutritional benefits, such as improving health and increasing acceptance by patients, adults, pets and children
05 / Enteric coated softgels
Enteric coated softgels is the best way to stabilize acid-sensitive drug products, improve tolerance, delay onset of action, as well as reduce poor aftertaste. Enteric coated softgels protect acid-labile APIs, and avoid gastric irritation and reflux. This is because the API is not delivered in the stomach - instead, it targets drug delivery in the small intestine which is preferred to treat intestinal disease.
Soft gelatin capsules with twist-off caps enable access to a measured dose for topical and oral applications.
Fun-trition with Gummygels
Our gummies comprise of gelatin, sweeteners, flavourings, and colourings. They can be molded into thousands of different shapes.
Gummies for pharmaceutical applications
Gummies are an innovative, more attractive alternative to deliver VMS, maintaining the effectiveness of the traditional pill.
We have a specialized facility for the production of gelatin-based nutritional gummies. Within this category, Softigel provides gummy treats for children, as well as nutritional supplements for kids and adults.
Hormone Replacement Therapy and Birth Control
Hormones in hormone replacement therapy and birth control demands strict controls to ensure the exact dosage and hormone balance.
Facilities for the development of hormone replacement therapy
Softigel is dedicated to hormone specialty pharmaceuticals that are produced under the highest standards and very controlled specifications. Softigel offers hormone products in softgels, tablets and G-tabs™.
Other Drug Delivery Forms
As well as softgel capsules, Softigel manufactures other pharmaceutical forms, such as syrups, suspensions, creams, drops and emulsions.
Omega-3 Fish Oils
Softigel is dedicated to the manufacture and research and development of omega-3 extracts from fish oil, sourced from the Pacific Ocean.
Our molecular distillation facility allows us to create an expanded line of products rich in EPA and DHA. Softigel formulates, manufactures, and markets 90% fish oil omega-3 pharmaceutical grade FDA approved for Rx products.
Tablets & Powders
We produce both tablets and powders for pharmaceutical applications.
Softigel tablets consist of a blend of active substances and excipients, usually in powder form, pressed or compacted from a powder into a
We´re very much interested in having an opportunity to present our company, product development services and unique softgel technologies that might be of added value for your company. Visit us during Cphi Frankfurt at stand 61D10
For more information contact us at:
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