Applikon Biotechnology is a world leader in developing and supplying advanced bioreactor systems for the production of vaccines, antibodies, tissues, bio-pharmaceuticals, nutraceuticals and biosimilars in the Pharmaceutical industry, as well as enzymes, food, feed, bio-fuel, bio-chemicals and bio-plastics for Industrial Biotechnology. We can guide you through the whole upstream process, from initial screening up to full-scale production, using the same platform. 

Applikon Biotechnology proudly promotes an improved Quality of Life. As a world leader in the development and supply of advanced bioreactor systems, Applikon passionately contributes to the Life Sciences. Our goal is to continuously introduce new technologies to the market, covering the spectrum from laboratory scale via pilot plant to production scale. In addition to advanced cultivation systems, our core business also comprises Process Control and Process Information Management systems. Large investments in R&D and in-house development and production enable us to be flexible and efficient when delivering the best solution for each individual customer.

Disposable bioreactors Designed on Demand

• Fully customizable to meet your specific bioprocessing needs
• Install any number of systems to fit your workspace
• Cultivate anywhere; no laminar flowhood, water supply or drain needed
• Several perfusion options for continuous bioprocessing

The AppliFlex ST is a fully customizable stirred tank single-use bioreactor. By using 3D printing technology, we can create any head plate configuration that is optimal for your process. With this single-use system there is no risk of cross contamination between runs. The pre-sterilized, ready-to-use bioreactor makes your life in the lab a lot easier. No more assembling and sterilization before you can start your culture. No more cleaning after the culture is finished. Save time and costs, execute more runs, and reduce your time-to-market.

The 3D printing production technology guarantees complete reproducibility between the different bioreactors guaranteeing exact and identical conditions between runs. The AppliFlex ST offers the flexibility that you need for your specific bioprocess and is available for both cell culture and microbial applications.

The AppliFlex ST can be used as single unit as well as parallel processing systems. The design of the AppliFlex ST is a scale down version of our larger laboratory scale systems guaranteeing an easy scale-up of your process from the 500 mL to the larger volume cultivations. The single-use system can be exchanged with a multi-use system whenever your process or workflow needs a different approach.

The AppliFlex ST features a fully removable topplate for operators to have easy access to the culture. Pouring into downstream processing vessels or other bioreactors has never been this easy. Optionally a closed lid is available which makes the vessel ready for transport, storage or freezing.

Water supply is not required to operate the AppliFlex ST, cooling and heating are done using electric elements, the condenser is cooled electrically as well. No expensive laminar flowhood is needed to operate the system, expect for operator handling.

The AppliFlex ST can easily be integrated in a DeltaV control installation using our V-Control software. This makes process transfer from the lab to production and from production to the lab very simple.