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The pharma industry briefing
The latest news, approvals and clinical trials you need to know about this month
Data:
News
in Numbers
$38.5bn
The amount that the global market for blood cancer therapeutics was valued at in 2018 according to BCC Research's report
21%
The median UK uptake of NICE-approved medicines in the first year after launch compared to comparator countries including the US, France and Germany
51%
The portion of global industry respondents that believe that drug pricing and reimbursement constraints will have the greatest negative impact on the pharmaceutical industry in 2019
$14.6bn
The value of digital health investment in 2018, almost $3 billion more than in 2017 according to a report from Startup Health Insights
236
The reported number of drugs, spanning all stages of development, in the age-related macular degeneration pipeline
Data:
News
in Numbers
$38.5bn
The amount that the global market for blood cancer therapeutics was valued at in 2018 according to BCC Research's report
51%
The portion of global industry respondents that believe that drug pricing and reimbursement constraints will have the greatest negative impact on the pharmaceutical industry in 2019
$14.6bn
The value of digital health investment in 2018, almost $3 billion more than in 2017 according to a report from Startup Health Insights
21%
The median UK uptake of NICE-approved medicines in the first year after launch compared to comparator countries including the US, France and Germany
236
The reported number of drugs, spanning all stages of development, in the age-related macular degeneration pipeline
Growth of cloud computing space offers immense opportunity for pharma in 2019
The total healthcare cloud computing market size is forecast to be almost $35bn in 2022, growing at a Compound Annual Growth Rate (CAGR) of 21.7% between 2018 and 2022 according to GlobalData’s recent report, ‘Cloud Computing in Healthcare – Thematic Research’
Source: GlobalData
NICE rejects Novartis’ migraine prevention drug Aimovig
Some migraine sufferers in the UK hoping to get access to Novartis’ new migraine prevention drug Aimovig are facing disappointment after NICE rejected it in draft guidance.
The cost-effectiveness watchdog says that it can’t recommend routine NHS use of Aimovig (erenumab) for people suffering at least four migraine episodes each month, even though it is only intended for use after three earlier oral treatments have failed.
Source: Pharmaphorum
Endometriosis study 'sheds light on links to infertility' say scientists
A new study has cast light on why some women with endometriosis experience infertility, with scientists saying the finding could lead to new treatment options.
South Korea and US teams say infertility could be linked to deficiency of a protein in womb.
Source: The Guardian
Researchers redesign a cancer-busting protein without the side effects
For patients with aggressive kidney and skin cancers, an immune-boosting protein called interleukin-2 (IL-2) can be a lifesaver. But the dose at which it fights cancer can also produce life-threatening side effects.
Now, scientists have used computer modeling to design a new protein from scratch that mimics IL-2’s immune-enhancing abilities, while avoiding its dangerous side effects. The protein has so far been tested only in animals, but it may soon enter human trials.
Source: Science
Eli Lilly to buy Loxo Oncology for $8bn
Eli Lilly has announced its intention to buy pioneering cancer treatment development company Loxo Oncology in a deal worth approximately $8bn.
The agreement will cost Lilly $235 per share in cash, in a bid to boost its oncology portfolio with drugs for patients with genomically defined cancers.
Source: Pharma Times
Approvals
Crizanlizumab (SEG101)
The US FDA has granted Breakthrough Therapy designation to Novartis’ crizanlizumab for the prevention of vaso-occlusive crises (VOCs) in patients of all genotypes with sickle cell disease.
Source: Pharmaphorum
Tyvyt (sintilimab)
Chinese regulator the National Medical Products Administration has approved Innovent's anti-PD-1 antibody Tyvyt forthe treatment of patients with classical Hodgkin's lymphoma that has relapsed or refractory after two or more lines of systemic chemotherapy.
Source: The Pharma Letter
Venity (romosozumab)
The Japanese Ministry of Health, Labor and Welfare has granted a marketing authorisation for Amgen’s osteoporosis bone-forming drug for the treatment of osteoporosis in patients at high risk of fracture.
Source: Market Watch
Stivarga (regorafenib)
Bayer’s Stivarga has received a final green light from the National Institute for Health and Care Excellence for use by the NHS to treat advanced liver cancer.
Source: The Pharma Times
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